Toxicology : Tobacco-Specific N-Nitrosamines : Recent Advances / Roger O. McClellan

By:

McClellan, Roger O [Editor]

Material type: Text

TextPublication details: New York : CRC Press, 1996Edition: 1st edDescription: 119-253 pages : illustrations ; 29 cmISBN:

9780849311567
084931156X

Subject(s):

DDC classification:

615.9 MCT

Contents:

1. Introduction

2. Formation and Analysis of Tobacco-Specific N-Nitrosamines

3. Synthesis of Tobacco-Specific N-Nitrosamines and Their Metabolites and Results of Related Bioassays

4. Endogenous Formation of Nitrosamines and Oxidative DNA-Damaging Agents in Tobacco Users

5. Recent Studies on Mechanisms of Bioactivation and Detoxification of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone (NNK), A Tobacco-Specific Lung Carcinogen

6. Epidemiology of Cancer by Tobacco Products and the Significance of TSNA

7. The Biological Significance of Tobacco-Specific N-Nitrosamines: Smoking and Adenocarcinoma of the Lung

8. Comparative Carcinogenicity, Metabolism, Mutagenicity, and DNA Binding of 7H-Dibenzo[c,g]carhazole and Dibenz[a,j]acridine

9. Concluding Remarks

Summary: This book presents critical assessments of subjects that are part of the advancing frontiers of toxicology and related basic scientific disciplines or issues that form the core of some of the most complex and intractable problems with which the toxicologist has to grapple.

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Holdings
Item type	Current library	Collection	Shelving location	Call number	Copy number	Status	Date due	Barcode
Books	KU Central Library	Rack No. : 30 Annex : 01 Shelve No. : A-03	Reference Section (Non-Issuable Books)	615.9 MCT 1996 (Browse shelf(Opens below))	C-1 (NI)	Not For Loan		53334

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Cover title
"Special issue"--Page [1]
"This book is a reproduction of Critical reviews in toxicology, volume 26, Issue 2"--Page [1]
Six papers presented at a symposium on tobacco-specific n-nitrosamines at the 16th International Cancer Congress, Oct.-Nov. 1994, New Delhi.

Includes bibliographical references and indexes.

1. Introduction

2. Formation and Analysis of Tobacco-Specific N-Nitrosamines

3. Synthesis of Tobacco-Specific N-Nitrosamines and Their Metabolites and Results of Related Bioassays

4. Endogenous Formation of Nitrosamines and Oxidative DNA-Damaging Agents in Tobacco Users

5. Recent Studies on Mechanisms of Bioactivation and Detoxification of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone (NNK), A Tobacco-Specific Lung Carcinogen

6. Epidemiology of Cancer by Tobacco Products and the Significance of TSNA

7. The Biological Significance of Tobacco-Specific N-Nitrosamines: Smoking and Adenocarcinoma of the Lung

8. Comparative Carcinogenicity, Metabolism, Mutagenicity, and DNA Binding of 7H-Dibenzo[c,g]carhazole and Dibenz[a,j]acridine

9. Concluding Remarks

This book presents critical assessments of subjects that are part of the advancing frontiers of toxicology and related basic scientific disciplines or issues that form the core of some of the most complex and intractable problems with which the toxicologist has to grapple.

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